Liverpool enter the tie after a 6‑0 win over Qarabag but have suffered defeats to Manchester City and Bournemouth. Key defender Wataru Endo is ruled out for the match, while Joe Gomez may start after a recent lay‑off. The return of midfielder Dominik Szoboszlai restores creative options, though long‑term absences of Isak, Frimpong, Bradley and Leoni limit rotation.
Brighton arrive at Anfield with only two wins in 15 matches, raising questions over manager Fabian Hurzeler. Their recent loss at Villa Park and a lack of energy have highlighted a downturn, while the club faces managerial upheavals across the league. The Seagulls will look to break the slump in front of a hostile crowd.